Table 2. Differential expression between neo-X and neo-Y alleles.
| Median log2(neo-X /neo-Y) | No. of genes | Significantly differentially expressed alleles** | ||||
|---|---|---|---|---|---|---|
| RNA-seq | DNA-seq | Both | neo-X biased | neo-Y biased | ||
| passing filter* | (% of genes) | (% of both) | (% of both) | |||
| d.alb OKNY-2 (Y2; youngest) | 0.0000 | 0.0123 | 2128 | 26 (1.2%) | 18 (69.2%) | 8 (30.8%) |
| d.alb 03 (Y1; medium) | 0.0498 | 0.0313 | 2391 | 37 (1.6%) | 28 (75.7%)† | 9 (24.3%) |
| d.alb KM55 (Y3; oldest) | 0.0580 | 0.0590 | 3181 | 168 (5.3%) | 115 (68.5%)† | 53 (31.5%) |
* Genes with <5 reads in both alleles are removed
** False discovery rate corrected p < 0.05 (Fisher's Exact Test)
† Significantly more neo-X biased genes p < 0.01 (Binomial Exact Test)