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. 2019 Dec 6;9:18545. doi: 10.1038/s41598-019-53867-y

Figure 9.

Figure 9

Relaxin-Wnt interaction modulates collagen secretion by Fibroblasts. Fibroblasts treated with TGFβ showed a 3-fold increase in collagen expression that was dramatically inhibited by RLX to 31% of control expression.(ad) DKK1 blocked RLX’s inhibitory effects of TGFβ mediated collagen expression (d–g); n ≥ 43 cells/group. *Indicates p < 0.05 compared to control. #Indicates p < 0.05 compared to RLX. 400x magnification, scale bars = 25 µm and apply to all panels.