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. 2019 Dec 6;2:457. doi: 10.1038/s42003-019-0704-z

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Fig. 6 — Bowtie2 aligned raw reads to a reference genome were translated to amino acids (AA) sequences as peptides reads, manually edited in the consensus protein pileups tool, and untranslated back to DNA reads for re-alignment in Bowtie2. This cyclic process continues until convergence.