Table 2.

Longitudinal associations between irritability at follow-up and annualized rates of change in structural covariance networks

NMF-networks	r	β	SE	t	p	p-FDR
N-1: Medial temporal lobe	−0.35	−0.36	<0.01	−4.46	<0.001	<0.001
N-7: Inferior frontal cortex	−0.21	−0.21	<0.01	−2.48	0.014	0.043
N-9: Temporal pole and medial orbitofrontal cortex	−0.28	0.28	<0.01	−3.36	0.001	0.008
N-11: Occipital cortex	−0.35	−0.34	<0.01	4.32	<0.001	<0.001
N-15: Lateral temporal cortex	−0.22	−0.23	<0.01	−2.70	0.008	0.038
N-17: Supramarginal gyrus	−0.21	−0.21	<0.01	−2.53	0.013	0.043
N-18: Lateral orbitofrontal cortex	−0.20	−0.20	<0.01	−2.45	0.016	0.043
N-20: Inferior temporal cortex	−0.24	−0.23	<0.01	−2.81	0.006	0.034
N-22: Superior temporal gyrus	−0.20	−0.21	<0.01	−2.44	0.016	0.043

Partial correlations (Pearson’s r; controlling for age, sex, and data quality), β (standardized regression coefficients), standard errors, t-statistics, uncorrected and FDR-corrected p values for significant associations between irritability at follow-up and annualized rate of change of CT. All analyses were conducted on a log transformation of irritability to improve normality and contained 132 degrees of freedom