Table 1.
Effects of stress-induced hyperglycemia on clinical outcomes.
| Outcomes | Glycemic gap | p | SHR | p | ||
|---|---|---|---|---|---|---|
| <80 mg/dL (n = 489) | >80 mg/dL (n = 53) | <1.1 (n = 267) | >1.1 (n = 275) | |||
| Mortality (n, %) | 181 (37) | 26 (49) | 0.087 | 96 (36) | 111 (40) | 0.247 |
|
Need for RRT (n, %) Shock incidence (n, %) |
116 (23.7) 183 (37.4) |
20 (37.7) 29 (54.7) |
0.025 0.014 |
62 (23) 96 (36) |
74 (27) 116 (42) |
0.287 0.112 |
| Need for MV (n, %) | 286 (58.4) | 36 (67.9) | 0.184 | 141 (52.8) | 181 (65.8) | 0.001 |
| Time on MV (days) | 4 (1 to 8) | 4.5 (2 to 8) | 0.117 | 3 (1 to 8) | 2 (4 to 8.5) | <0.001 |
| LOS, hospital (days) | 20 (10 to 35) | 20 (10 to 34.7) | 0.585 | 19 (10.7 to 32.5) | 21 (9 to 38) | 0.263 |
| LOS, ICU (days) | 7 (3 to 12) | 7.5 (4.25 to 11) | 0.126 | 6 (3 to 11) | 8 (4 to 12) | 0.005 |
| ICU readmission (n, %) | 62 (12.6) | 6 (11.3) | 0.770 | 30 (11.2) | 38 (13.8) | 0.339 |
SHR: stress hyperglycemia ratio; RRT: renal replacement therapy; MV: mechanical ventilation; LOS: length of stay; ICU: intensive care unit. Glycemic gap was calculated by the difference between the serum glucose at ICU admission and the estimated mean blood glucose derived from HbA1c. SHR was defined by the ratio between serum glucose at admission and the estimated mean blood glucose derived from HbA1c. Values are mean ± SD or median and interquartile range.