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. 2019 Dec 6;3:32. doi: 10.1038/s41698-019-0103-4

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Fig. 6 — IFN-γ signaling in high-grade serous ovarian cancer (HGSOC) tumors. a, b Associations determined by regression analysis between mRNA levels of CXCL10, CXCL11, or IFI16 with IFN-γ a, and between IFI16 with CXCL10 or CXCL11 b in HGSOC samples from the TCGA database. c Hierarchical clustering of HGSOC tumor specimens profiled in the TCGA based on CXCL10, CXCL11, and IFI16 mRNA expression levels identified two groups of patients (samples). Columns correspond to individual tumors. d Disease-free survival analysis for patients profiled in the TCGA and grouped as having “low” or “high” (relative to their median values) combined expression levels for the IFN-γ-regulated genes CXCL10, CXCL11, and IFI16. The P value is for Cox proportional hazard regression analysis.