Table 1.
Characteristics of the Study Population.
| Characteristics | Normal (N) | Pre-perimetric Glaucoma (PPG) | p-value N v. PPG | Perimetric Glaucoma (PG) | p-value N v. PG |
|---|---|---|---|---|---|
| Number of participants (eyes) | 124 (245) | 245 (420) | N/A | 192 (289) | N/A |
| Age (years) | 58.4 ± 9.3 | 61.0 ± 9.5 | 0.001 | 63.0 ± 9.6 | <0.001 |
| Female (%) | 64.2 | 60.9 | 0.388 | 61.6 | 0.537 |
| African Decent (%) | 6.5 | 12.9 | 0.009 | 10.4 | 0.110 |
| Axial length (mm) | 23.7 ± 1.0 | 24.3 ± 1.3 | <0.001 | 24.3 ± 1.3 | <0.001 |
| Corneal thickness (µm) | 562 ± 33 | 558 ± 37 | 0.180 | 545 ± 37 | <0.001 |
| IOP (mmHg) | 14.9 ± 2.2 | 16.2 ± 2.8 | 0.010 | 17.3 ± 3.3 | <0.001 |
| VF MD (dB) | −0.0 ± 1.1 | −0.5 ± 1.1 | 0.055 | −4.7 ± 4.4 | <0.001 |
| VF PSD (dB) | 1.5 ± 0.3 | 1.8 ± 0.5 | 0.250 | 5.7 ± 4.1 | <0.001 |
| Overall NFLT (µm) | 100.5 ± 8.4 | 96.0 ± 10.0 | <0.001 | 84.2 ± 11.3 | <0.001 |
The characteristics of the study participants were averaged over the 4 consecutive study visits except for axial length and central corneal thickness, which were only measured at baseline. IOP = intraocular pressure; VF = visual field; MD = mean deviation; PSD = pattern standard deviation; NFLT = nerve fiber layer thickness.