Fig. 5.

vHC-PrL synchrony during fear recall and in the home cage. a Phase coherence between theta oscillations in the vHC and PrL was significantly lower in hM3Dq mice during tone/context recall. b The vHC LFP led the PrL LFP in all frequency bands during tone/context recall in mCherry mice, while CNO injections severely disrupted this effect selectively in the theta frequency band in hM3Dq mice (black dashed line = chance). c vHC theta strongly led PrL theta during tone/context recall in mCherry mice, and this effect was abolished in hM3Dq mice. d vHC theta-gamma coupling, e theta power, f slow gamma power, and g theta phase coherence between the vHC and PrL did not significantly differ between hM3Dq and mCherry animals in the home cage, either before or after CNO injections