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. 2019 May 9;44(12):2045–2053. doi: 10.1038/s41386-019-0414-8

Fig. 2.

Fig. 2

The mediating role of gray-matter volume (GMV) in the relationship between oxytocin receptor gene (OXTR) methylation and insecure attachment style in childhood maltreatment. a Relationship between GMV and OXTR methylation. The vertical axis indicates OXTR methylation levels at CpG 5,6, whereas the horizontal axis indicates GMV estimates in the left orbitofrontal cortex (OFC). b Relationship between GMV and insecure attachment style. The vertical axis indicates the insecure attachment style score, whereas the horizontal axis indicates GMV estimates in the left OFC. c Path model on the mediation effect of GMV on the relationship between OXTR methylation and insecure attachment style (*P < 0.05; ***P < 0.001)