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Neutrophil phagocytosis and microbicidal process. Panel A illustrates binding and phagocytosis of a microbe opsonized with antibody or serum complement. Phagocytosis triggers production of superoxide (O2•–) from which other secondarily derived ROS are formed, including hydrogen peroxide (H2O2) and hypochlorous acid (HOCl). Panel B is a transmission electron micrograph of a human neutrophil that has phagocytosed numerous Staphylococcus aureus (Microbe).
