Table 1.
Baseline Characteristics and Associations With Early Post‐AVR Systolic and Diastolic Blood Pressures
| All Patients (n=2897) | Correlation (r) With Early Post‐AVR SBP | Correlation (r) With Early Post‐AVR DBP | TAVR (n=1794) | SAVR (n=1103) | |
|---|---|---|---|---|---|
| Clinical | |||||
| Age, y | 81±7 | 0.06* | −0.05* | 81±7 | 81±6 |
| Women, % | 46 | 0.11* | −0.00 | 47 | 45 |
| Body mass index, kg/m2 | 29±6 | 0.00 | 0.02 | 29±6 | 29±6 |
| NYHA class III/IV, % | 72 | −0.06* | −0.11* | 76 | 67 |
| STS score | 6.3±3.9 | 0.03 | −0.13* | 6.9±4.4 | 5.4±2.6 |
| Diabetes mellitus, % | 37 | 0.03 | −0.05* | 36 | 38 |
| Creatinine >2 mg/dL, % | 3 | 0.04* | 0.00 | 3 | 3 |
| History of hypertension, % | 93 | 0.08* | −0.01 | 93 | 92 |
| Peripheral vascular disease, % | 35 | 0.02 | −0.04* | 36 | 33 |
| Prior stroke, % | 10 | −0.05* | −0.01 | 10 | 9 |
| COPD, % | 43 | −0.03 | −0.01 | 46 | 37 |
| Home oxygen, % | 11 | −0.07* | −0.09* | 14 | 5 |
| Coronary artery disease, % | 70 | −0.03 | −0.08* | 71 | 68 |
| Previous myocardial infarction, % | 20 | −0.07* | −0.03 | 22 | 18 |
| Atrial fibrillation/flutter, % | 35 | −0.11* | −0.00 | 37 | 32 |
| Cirrhosis, % | 1.3 | −0.05* | −0.02 | 1.6 | 1.0 |
| Immunosuppressive therapy, % | 10 | −0.02 | −0.01 | 10 | 9 |
| Frailty | |||||
| BMI <21 kg/m2 | 4.7 | −0.01 | 0.02 | 5.6 | 3.3 |
| 5‐m gait speed (seconds) | 8.8±12.4 | −0.03 | −0.04* | 9.5±15.3 | 7.7±5.1 |
| Grip strength < frail threshold | 66 | −0.03 | −0.06* | 67 | 65 |
| MMSE score | 27±3 | 0.01 | 0.08* | 27±3 | 27±3 |
| Wheelchair bound | 4.5 | 0.02 | −0.05* | 5.9 | 2.3 |
| ADLs (# independent) | 5.8±0.8 | −0.00 | 0.06* | 5.7±0.9 | 5.9±0.6 |
| CT measurements | |||||
| Ascending aortic dimension, mm | 33±3 | −0.04* | 0.04 | 33±3 | 33±3 |
| Sinotubular junction dimension, mm | 28±3 | −0.07* | 0.04 | 28±3 | 28±3 |
| Sinuses of Valsalva width, mm | 32±5 | −0.07* | 0.03 | 32±5 | 32±3 |
| Pre‐AVR vascular parameters | |||||
| Heart rate, bpm | 72±12 | −0.10* | 0.01 | 72±12 | 71±13 |
| Systolic blood pressure, mm Hg | 136±20 | 0.32* | 0.14* | 134±19 | 138±21 |
| Diastolic blood pressure, mm Hg | 69±11 | 0.07* | 0.28* | 68±10 | 71±11 |
| Mean arterial pressure, mm Hg | 91±12 | 0.22* | 0.25* | 90±11 | 93±13 |
| Pulse pressure, mm Hg | 67±18 | 0.31* | −0.01 | 66±18 | 67±19 |
| Systemic arterial compliance | 0.7±0.3 | −0.14* | −0.00 | 0.7±0.3 | 0.7±0.3 |
| Systemic vascular resistance | 2902±935 | 0.00 | 0.04 | 2896±954 | 2908±911 |
| Valvuloarterial impedance | 4.7±1.4 | 0.04 | 0.10* | 4.7±1.4 | 4.8±1.4 |
| Valves implanted | |||||
| Size of SAVR valve | ··· | −0.11* | 0.02 | ··· | 22.9±2.1 |
| Type of TAVR valve (CoreValve %) | ··· | 0.04 | 0.04 | 92 | ··· |
| Size of TAVR valve | ··· | −0.08* | 0.06* | 28.5±1.9 | ··· |
Data shown as percentage or mean±SD. ADL indicates activities of daily living; AVR, aortic valve replacement; BMI, body mass index; COPD, chronic obstructive pulmonary disease; MMSE, mini‐mental status examination; NYHA, New York Heart Association; SAVR, surgical aortic valve replacement; STS, Society of Thoracic Surgeons; TAVR, transcatheter aortic valve replacement.
*
P<0.05.