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. 2019 Oct 16;8(21):e013287. doi: 10.1161/JAHA.119.013287

Table 3.

Association Between Tertiles of Urinary Sodium (Na) and Blood Pressure in the Pooled Data From Both Visits

Measurement Methods Systolic Blood Pressure Diastolic Blood Pressure
Tertile 1 Tertile 2 βa (95% CI) Tertile 3 βa (95% CI) Tertile 1 Tertile 2 βa (95% CI) Tertile 3 βa (95% CI)
Estimated daily Na+ from first morning urine sample (N=651)
Unadjusted Ref 0.33 (−1.33, 1.99) 0.81 (−1.69, 3.31) Ref 0.28 (−0.38, 0.93) 0.28 (−1.48, 2.05)
Adjusted for visit, age, sex, and BMI Ref 0.01 (−0.98, 0.99) −0.64 (−2.29, 1.00) Ref 0.02 (−1.01, 1.06) −0.34 (−0.81, 0.13)
Full adjusted modelb Ref 0.04 (−1.00, 1.09) −0.72 (−2.41, 0.97) Ref −0.04 (−1.00, 0.92) −0.50 (−0.98, −0.02)
Estimated daily Na+ from second morning urine sample (N=739)
Unadjusted Ref 2.84 (1.45, 4.24) 3.22 (0.48, 5.96) Ref 1.75 (0.60, 2.89) 1.58 (−0.61, 3.77)
Adjusted for visit, age, sex, and BMI Ref 3.03 (1.32, 4.72) 2.81 (0.29, 5.33) Ref 1.78 (0.43, 3.13) 1.44 (−1.78, 3.05)
Full adjusted modelb Ref 3.01 (1.31, 4.70) 2.77 (0.41, 5.14) Ref 1.70 (0.42, 2.98) 1.34 (−0.19, 2.86)
Measured 24 h urinary Na+ (N=733)
Unadjusted Ref 0.71 (−2.12, 3.54) 0.56 (−2.10, 3.21) Ref −0.17 (−1.70, 1.37) 0.03 (−1.63, 1.70)
Adjusted for visit, age, sex, and BMI Ref 0.83 (−2.26, 3.92) 0.85 (−2.26, 3.92) Ref −0.20 (−1.81, 1.41) −0.13 (−1.71, 1.46)
Full adjusted modelb Ref 0.74 (−2.21, 3.70) 0.81 (−1.92, 3.53) Ref −0.21 (−1.79, 1.37) −0.11 (−1.74, 1.51)
Complete measured 24 h urinary Na+ (N=733)
Unadjusted Ref 0.98 (−1.77, 3.72) 0.51 (−1.66, 3.72) Ref 0.14 (−1.43, 1.71) 0.09 (−1.21, 1.39)
Adjusted for visit, age, sex, and BMI Ref 1.55 (−1.55, 4.66) 1.25 (−1.26, 3.76) Ref 0.22 (−1.38, 1.82) 0.04 (−1.20, 1.30)
Full adjusted modelb Ref 1.44 (−1.42, 4.31) 1.23 (−1.16, 3.62) Ref 0.26 (−1.24, 1.77) 0.08 (−1.19, 1.35)

BMI indicates body mass index.

First morning void was collected on the second day and vice versa. Estimated daily Na+ from first morning urine; tertile 1: <110 mmol/d, tertile 2: ≥110 to <129 mmol/d; tertile 3: ≥129 to 322 mmol/d. Estimated daily Na+ from second morning urine; tertile 1: <112.5 mmol/d, tertile 2: ≥112.5 to <131.9 mmol/d; tertile 3: ≥131.9 to 333 mmol/d. Measured 24‐h urinary Na+; tertile 1: <96.2 mmol/d, tertile 2: ≥96.2 to <152.1 mmol/d; tertile 3: ≥152.1 to 468 mmol/d.

a

Refers to differences in mean blood pressure (in mm Hg) of participants compared with reference category, obtained from linear regression.

b

Model adjusted for visit, age, sex, BMI, physical activities and smoking status, alcohol consumption, sleep hours, religion, and household wealth.