Figure 1.

Forest plot on the risk of all‐cause mortality at 3 months between patients randomized to mechanical thrombectomy plus best medical treatment or best medical treatment alone. BMT indicates best medical therapy; DAWN, DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake‐Up and Late Presenting Strokes Undergoing Neurointervention with Trevo; DEFUSE, Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke; ESCAPE, Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times; EXTEND‐IA, Extending the Time for Thrombolysis in Emergency Neurological Deficits — Intra‐Arterial; MR CLEAN, Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands; MT, mechanical thrombectomy; PISTE, Pragmatic Ischaemic Stroke Thrombectomy Evaluation; RESILIENT, Randomisation of endovascular treatment with stent‐retriever and/or thromboaspiration versus best medical therapy with acute ischaemic stroke due to large vessel occlusion; REVASCAT, Randomized Trial of Revascularization with Solitaire FR Device versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting within Eight Hours of Symptom Onset; SWIFT PRIME, Solitaire with the Intention for Thrombectomy as Primary Endovascular Treatment; THERAPY, The Randomized, Concurrent Controlled Trial to Assess the Penumbra System's Safety and Effectiveness in the Treatment of Acute Stroke; THRACE, Thrombectomie des Artères Cerebrales.