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. 2019 Oct 23;8(21):e012535. doi: 10.1161/JAHA.119.012535

Table 3.

HR With 95% CI for the Association Between HADS‐D (Continuous, 3 Categories, Combined Values from HUNT2 and HUNT3), and Risk of AAAa

Factors No. of AAA n Univariable HR (95% CI) Multivariable HR (95% and CI)b
HADS‐D, continuous (0–21) 622 1.03 (1.01–1.06) 1.02 (0.99–1.04)
P for trend 0.007 0.16
HADS‐D (3 categories)
<8 513 1.00 1.00
8–10 80 1.55 (1.24–1.94) 1.43 (1.15–1.79)
≥11 29 1.21 (0.81–1.79) 1.03 (0.70–1.53)
P for trend 0.0005 0.007
HADS‐D (combined)c
Never 120 1.00
Intermittent 31 1.41 (0.95–2.1)
Persistent 11 1.50 (0.81–2.8)
P for trend 0.13

Number of individuals (continuous vs 3 categories), n=50 657. Number of individuals (combined categories), n=20 366. AAA, abdominal aortic aneurysm; HADS‐D, Hospital Anxiety and Depression Scale–Depression; HR, hazard ratios; HUNT, Norwegian Nord‐Trøndelag Health Study.

a

HR estimates with 95% CIs calculated in a Cox proportional hazard regression model with attained age as time scale.

b

HR estimates with 95% CI for all 3 HADS‐D variables (continuous vs 3 categories, combined categories) in separate models, but equally adjusted for age at HADS‐D measure (HUNT participation), sex, diabetes mellitus, body mass index, coronary heart disease, hypertension, total cholesterol, and smoking.

c

Combined categories of HADS‐D were defined as, never (<8, <8), intermittent (<8,≥8 or ≥8,<8), persistent (≥8, ≥8).