Table 1.
Characteristic | n (%) or median (IQR) |
---|---|
Sex | |
Male | 70 (89) |
Female | 9 (11) |
Age (years) | 44 (34.5 to 53) |
Cumulative TDF exposure (years) | 3.5 (1.5 to 4.75) |
Pre-switch TDF regimen | |
TDF/FTC/† | 38 (48) |
TDF/FTC/RPV | 18 (23) |
TDF/FTC/EFV | 15 (19) |
TDF/FTC/E/COBI | 8 (10) |
Post-switch TAF regimen | |
TAF/FTC/† | 57 (72) |
TAF/FTC/RPV | 12 (15) |
TAF/FTC/E/COBI | 10 (13) |
COBI cobicistat, E elvitegravir, EFV efavirenz, eGFR estimated glomerular filtration rate, FTC emtricitabine, RPV rilpivirine, TAF tenofovir alafenamide, TDF tenofovir disoproxil fumarate
†These regimens contained a third agent not otherwise listed in the table. In over three quarters of patients, both pre- and post-switch, the third agent was dolutegravir