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. 2019 Dec 7;20:591. doi: 10.1186/s12891-019-2977-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a H&E staining showed the typical pathological status of OA and RA hyperplastic synovial tissues. b Masson staining validated that the hyperplastic fibroblast is more prominent in an RA synovium. c The sorted number of FLS using the CD45⁻CD31⁻CD146⁻CD235a⁻CD90⁺PDPN⁺ sorting strategy. d The sorted OA and RA FLS exhibited a classic spindle-shaped fibroblastic morphology. e The comparison of markers of FLS in both OA FLS and RA FLS, as measured by qRT-PCR. Each bar in the figure represents the mean ± SEM of triplicates. *P < 0.05