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Distinct actin cytoskeleton protrusions in primary T-cells. (A) Mouse CD4+ T-cells form actin foci during activation (white arrows) in the periphery of the IS (red arrows). (B) Actin foci (white arrows and yellow in 3D reconstruction in images) form in the centre of the contact interface with a well-defined life-time distribution (bar graph). Scale bars: 5 µm (A), 1 µm (B).
