Table 4.
Multivariable Logistic Regression: Most Important Determinants of Influence on Cognitive Impairment (–2SD) for Specific Domains
Domain | Executive Functioning | Memory | Language | Visuospatial Functioning | Psychomotor Speed | |||||
---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95%CI) | P Value | OR (95% CI) | P Value | |
Volumes T2-FLAIR (mm 3) | 1.000012 (1.000006-1.000018) | <.0005 | 1.000011 (1.000004-1.000018) | .001 | 1.000009 (1.000001-1.000016) | .026 | 1.000005 (0.999998-1.000011) | .141 | 1.000005 (0.999998-1.000011) | .143 |
IDH-mutation | 0.463 (0.192-1.117) | 0.087 | 0.175(0.054-0.569) | 0.004 | 0.360 (0.104-1.248) | 0.107 | 0.185(0.063-0.542) | 0.002 | 0.338 (0.138-0.827) | 0.018 |
Abbreviations: FLAIR, fluid-attenuated inversion recovery; IDH, isocitrate dehydrogenase; OR, odds ratio.