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| SGLT-2 Inhibitor | Bioavailability | Time to Peak Action (Hours) | Half-Life (Hours) | SGLT-2 Inhibitor Selectivity Over SGLT-1 |
|---|---|---|---|---|
| Canagliflozin | ~ 65% | 1–2 h | 11–13 h | 1:414 |
| Dapagliflozin | ~ 78% | 1–1.5 h | 13 h | 1:1200 |
| Empagliflozin | ~75% | 1.5 h | 13 h | 1:2500 |
| Ertugliflozin | 70–90% | 0.5–1.5 h | 11–17 h | 1:2000 |
Abbreviation: SGLT-2, sodium-glucose co-transporter 2.
