(A) Example cavitation duty cycle curves, fit to the observed relative frequency of spectra containing cavitation emissions, observed while insonating coupling baths containing various concentrations of magnetite nanoparticles in a high duty cycle regime. (B) The 0.5 cavitation duty cycle threshold power, derived from all fits, including those shown in (A), as a function of nanoparticle concentration. This threshold decreases linearly with pressure at a rate of 308 WmM−1. (C) Cavitation dose estimated for each acoustic power level for several coupling bath compositions. As nanoparticle concentration increases, the number and spectral power of cavitation events increases, increasing thermal dose.