Extended Data Fig. 6. Analysis of the effect of Vif K50E mutation on A3G degradation in cells.
Western blot (a) and quantified A3 levels relative to No Vif (b) show that the Vif K50E mutant could not induce A3F degradation in the presence of either CBFβ WT or CBFβ E54K but could induce A3G degradation (mean ± s.d.; n=3 biologically independent experiments).