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. Author manuscript; available in PMC: 2020 Jun 2.
Published in final edited form as: Nat Struct Mol Biol. 2019 Dec 2;26(12):1167–1175. doi: 10.1038/s41594-019-0344-5

Figure 6. Summary of conformational changes described in text between closed and various open Env conformations (see also Supplementary Video).

Figure 6.

Env conformations are indicated, along with the complex from which the Env structure was derived. a, Closed Env trimer conformation (PDB 5CEZ). b, Partially-open sCD4-bound Env conformation (PDB 6CM3). c, Open conformation A (intermediate between partially-open and fully-open sCD4-bound Env conformations). d, Fully-open sCD4-bound Env conformation B.