(A) Frequency regions selected for PER2::LUC monitoring are depicted
(black: apical turn; red: middle turn; blue: basal turn). Scissors indicate the
areas where the cochlea was cut and the numbers represent the corresponding
frequencies along the tonotopic axis (kHz). (B) Amplitude, (C) phase and (D)
period of PER2::LUC rhythms in the three different cochlear regions as depicted
in the diagram (C: whole cochlea, A: apical turn, M: middle turn and B: basal
turn). The color of each histogram corresponds to the frequency region shown in
Fig. 3A. The results are presented as mean ± SEM, n =
7–13 cochleae, * = p < 0.05, *** =
p < 0.001.