Demographic data |
|
Total number 10/2011-05/2016 |
n = 38 |
Age (median) |
50 years |
Male |
n = 16 (42%) |
Female |
n = 22 (58%) |
Cirrhosis |
n = 4 (11%) |
Ascites |
n = 3 (8%) |
Hepatic encephalopathy (grade 1) |
n = 1 (3%) |
MELD, median (range) |
16 (6-23) |
Other autoimmune disease |
n = 21 (55%) |
Simplified AIH score (available for n = 26) |
|
Definite AIH (points ≥ 7) |
n = 7 (27%) |
Probable AIH (points > 6) |
n = 8 (31%) |
No AIH (points ≤ 5) |
n = 11 (42%) |
Liver histology (available for n = 28) |
|
AIH typical |
n = 8 (29%), interface hepatitis n = 3 (11%) |
Inconclusive |
n = 7 (25%) |
Not performed |
n = 10 (36%) |
Immunosuppressive therapy |
|
Prednisolone (mg), median (range) |
60 mg (50-100 mg) |
Prednisolone therapy duration (days), median (range) |
180 days (60-1080 days) |
Azathioprine (mg), median (range) |
100 mg (50-200 mg) |
Azathioprine start after weeks, median (range) |
3 weeks (1-12 weeks) |
Azathioprine intolerance |
n = 11 (29%) |
Conversion to MMF |
n = 11 (29%) |
Conversion to Everolimus |
n = 2 (5%) |
Outcome |
|
Survival |
n = 38 (100%) |
Infection |
n = 1 (3%) |
Liver transplantation |
n = 0 (0%) |