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. 2019 Nov 26;2019:1790908. doi: 10.1155/2019/1790908

Figure 4.

Figure 4

Involvement of TLR2 and TLR4 in the production of IL-6 (a), IL-10 (b), IL-12 (c), IFN-γ (d), and TNF-α (e) by human polymorphonuclear neutrophils (PMN) stimulated or not with gp43 from P. brasiliensis. Cells were incubated in the absence or presence of anti-TLR2 and anti-TLR4 antibodies, individually or in combination, for 2 h. PMNs were then stimulated or not with gp43 (20 ng/ml) during 4 h, and cytokine concentrations (pg/ml) were measured in the supernatant culture. Results are expressed as median using data from 7 women tested, considering p < 0.05.