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. 2019 Nov 25;2019:2345658. doi: 10.1155/2019/2345658

Figure 1.

Figure 1

PRMT5 was upregulated and renal function deteriorated after renal ischemia/reperfusion. SCr levels (a) and BUN levels (b) were detected after ischemia and different reperfusion times, 0 h, 12 h, and 24 h. Scores for the histological appearance of acute tubular necrosis (c) and representative images of mouse kidney H-E staining (original magnification ×400) (d). (e) PRMT5 protein levels were detected by western blot analysis after ischemia and different reperfusion time. (f) PRMT5 mRNA levels were detected by real-time RT-PCR after ischemia and different reperfusion time. Values were expressed as the mean ± SEM. ∗P < 0.05, relative to the sham group; #P < 0.05, relative to the group at reperfusion 12 h, n = 6. BUN: blood urea nitrogen; SCr: serum creatinine; H-E: hematoxylin-eosin; I/R: ischemia-reperfusion.