TABLE 2.
Impact of demographics, and number and type of comorbidities on achieving minimal important difference in exercise capacity
| Demographic | COPD (n=193) | ILD (n=48) |
| Age group | ||
| <65 years | 74.5% | 94.7%** |
| ≥65 years | 61.6% | 51.7% |
| mMRC score | ||
| 0–1 | 71.4% | 100% |
| 2 | 46.4% | 33.3% |
| 3–4 | 68.1% | 70.0% |
| Sex | ||
| Female | 67.4% | 69.6% |
| Male | 63.5% | 68.0% |
| Oxygen use | ||
| Yes | 66.3% | 76.9% |
| No | 64.2% | 65.7% |
| Type of comorbidity | ||
| Circulatory | ||
| Yes | 63.3% | 53.8%* |
| No | 69.2% | 86.4% |
| Digestive | ||
| Yes | 65.9% | 65.4% |
| No | 64.8% | 72.7% |
| Endocrine and metabolic | ||
| Yes | 66.3% | 62.5% |
| No | 64.4% | 75.0% |
| MSK and connective tissue | ||
| Yes | 59.5% | 47.4%* |
| No | 69.3% | 82.8% |
| Mental and behavioural | ||
| Yes | 67.1% | 65.2% |
| No | 64.3% | 72.0% |
| Number of comorbidities | ||
| 0–2 | 65.8% | 87.5% |
| 3–4 | 70.7% | 58.3% |
| ≥5 | 54.8% | 62.5% |
Data are presented as the percentage of responders achieving an increase in 6-min walking distance ≥30 m. ILD: interstitial lung disease; mMRC: modified Medical Research Council dyspnoea scale; MSK: musculoskeletal. *: p<0.05; **: p<0.01.