TABLE 3.
Impact of demographics, number and type of comorbidity on achieving minimal important difference in health-related quality of life
| Demographic | COPD (n=144) | ILD (n=36) |
| Age group | ||
| <65 years | 73.8% | 70.6% |
| ≥65 years | 61.8% | 63.2% |
| mMRC score | ||
| 0–1 | 28.6% | 50.0% |
| 2 | 63.6% | 100.0% |
| 3–4 | 71.7% | 64.0% |
| Sex | ||
| Female | 74.3%* | 81.3% |
| Male | 56.8% | 55.0% |
| Oxygen use | ||
| Yes | 61.6% | 72.4% |
| No | 69.0% | 43.0% |
| Type of comorbidity | ||
| Circulatory | ||
| Yes | 60.4% | 73.7% |
| No | 75.0% | 58.8% |
| Digestive | ||
| Yes | 69.7% | 61.9% |
| No | 61.5% | 73.3% |
| Endocrine and metabolic | ||
| Yes | 62.0% | 82.4% |
| No | 68.5% | 52.6% |
| MSK and connective tissue | ||
| Yes | 67.8% | 69.2% |
| No | 63.5% | 65.2% |
| Mental and behavioural | ||
| Yes | 70.2% | 70.6% |
| No | 62.9% | 63.2% |
| Number of comorbidities | ||
| 0–2 | 69.0% | 64.3% |
| 3–4 | 64.3% | 58.8% |
| ≥5 | 60.0% | 100% |
Data are presented as the percentage of responders achieving an increase in Chronic Respiratory Disease Questionnaire score ≥0.5 units. ILD: interstitial lung disease; mMRC: modified Medical Research Council dyspnoea scale; MSK: musculoskeletal. *: p<0.05.