Table 4. GRADE evidence profile according to WHOQOL-Bref domains of the studies included in meta-analysis.
Factors which would downgrade the quality of evidence | Factors which would upgrade the quality of evidence | Summary of results | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
WHOQOL-Bref outcomes (n) | Limitations | Inconsistency | Indirectness | Imprecision | Publication bias | Large effect | Dose-response | Confounders | Other | Quality of evidence/response | Comments |
Physical domain 7 studies (3,402) |
Undetected (0) | Detected I2 = 51.42 (-1) |
Undetected (0) | Undetected Power of meta-analysis ≥ 80% (0) |
Undetected (0) | N/A (0) | N/A (0) | Confounder increased confidence in estimated effects in all studies (+1) | Detected representative samples (+1) | Moderate | +1 due to sample characteristics |
Psychological domain 7 studies (3,402) |
Undetected (0) | Detected I2 = 20.83 (0) |
Undetected (0) | Undetected Power of meta-analysis ≥ 80% (0) |
Undetected (0) | N/A (0) | N/A (0) | Confounder increased confidence in estimated effects in all studies (+1) | Detected representative samples (+1) | High | +1 due to sample characteristics |
Social relationship domain 7 studies (3,402) |
Undetected (0) | Detected I2 = 51.38 (-1) |
Undetected (0) | Detected Power of meta-analysis = 15.36% (-2) |
Undetected (0) | N/A (0) | N/A (0) | Confounder increased confidence in estimated effects in all studies (+1) | Detected representative samples (+1) | Low | +1 due to sample characteristics |
Environment domain 7 studies (3,402) |
Undetected (0) | Undetected I2 = 0.0 (0) |
Undetected (0) | Detected Power of meta-analysis = 45% (-2) |
Undetected (0) | N/A (0) | N/A (0) | Confounder increased confidence in estimated effects in all studies (+1) | Detected representative samples (+1) | Low | +1 due to sample characteristics |
N/A = not applicable or not rated.