Table 3. Correlation between genome-wide and pyrosequencing methylation data.
Δβ | Pyrosequencing | Mann-Whitney U test | Linear regression | ||||
---|---|---|---|---|---|---|---|
ProbeID | Gene | ChAMP | RnBeads | Log2(meancontrol/meancase) | p-value | R2 | p-value |
cg10633981 | C11orf58 | -0.167 | -0.166 | 0.043* | < 0.0001 | 0.319 | < 0.0001 |
cg19933985 | IGR | -0.145 | -0.148 | -0.072 | < 0.0001 | 0.675 | < 0.0001 |
cg11049075 | HDAC5 | -0.090 | -0.099 | -0.040 | 0.0004 | 0.130 | 0.016 |
cg24449302 | MAP2K1 | 0.063 | 0.088 | 0.178 | 0.0001 | 0.277 | 0.0002 |
cg17479131 | LOC401431 | 0.145 | 0.133 | -0.352* | 0.002 | 0.021 | 0.3433 |
cg09844907 | MPV17L | 0.048 | 0.140 | 0.095 | 0.5651 | 0.045 | 0.1731 |
Discordant.