Table 1. Prevalence of anxiety disorders and its association with abuse of/dependence on legal and illicit substances in young adults from the city of Pelotas, Rio Grande do Sul, Brazil.

		Legal substances				Illicit substances
		Tobacco		Alcohol		CNS depressants		Stimulants		Cannabis		Crack cocaine
	n (%)	n (%)	p-value	n (%)	p-value	n (%)	p-value	n (%)	p-value	n (%)	p-value	n (%)	p-value
GAD	152 (9.7)	55 (36.2)	0.001	49 (32.2)	0.139	14 (9.2)	< 0.001	10 (6.6)	0.006	13 (8.6)	0.001	3 (2.0)	0.425
OCD	51 (3.3)	22 (43.1)	0.004	22 (43.1)	0.012	4 (7.8)	0.032	7 (13.7)	< 0.001	8 (15.7)	0.001	2 (3.9)	0.167
PD	39 (2.5)	16 (41.0)	0.03	12 (30.8)	0.708	8 (20.5)	< 0.001	2 (5.1)	0.674	1 (2.6)	0.803	1 (2.6)	0.872
SAD	63 (4.0)	23 (36.5)	0.044	22 (34.9)	0.184	7 (11.1)	< 0.001	4 (6.3)	0.166	7 (11.1)	0.031	2 (3.2)	0.276
Agoraphobia	192 (12.3)	71 (37.0)	< 0.001	62 (32.3)	0.084	11 (5.7)	0.003	11 (5.7)	0.014	17 (8.9)	0.006	4 (2.1)	0.242
PTSD	32 (2.1)	16 (50.0)	0.002	11 (34.4)	0.443	5 (15.6)	< 0.001	5 (15.6)	< 0.001	5 (15.6)	0.011	4 (12.5)	< 0.001
Overall	1,560 (100.00)	398 (24.9)	-	419 (26.9)	-	37 (2.2)	-	43 (2.8)	-	73 (4.7)	-	16 (1.0)	-

CNS = central nervous system; GAD = generalized anxiety disorder; OCD = obsessive-compulsive disorder; PD = panic disorder; PTSD = posttraumatic stress disorder; SAD = social anxiety disorder.

All p-values obtained using Fisher’s exact test for the association between each anxiety disorder and abuse/dependence of each substance.

Disruptors (hallucinogens) were not included in the table because only four participants reported intake of these substances.