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Differentially Expressed Genes after RUNX1-ETO Knockdown Are Regulated by Different TF Networks
(A) Top panel: data analysis strategy. Transcriptional network of downregulated (blue) non-TF (effector) genes after RUNX1-ETO knockdown (top rows) connected to genes encoding TF families (bottom rows) as determined by digital footprinting and CHi-C. Arrows going outward can come from any TF family within a group; incoming arrows are specific for each gene.
(B) Node and edge attributes.
