Table 2.
The Nijmegen hemostasis assay parameters in patients with a plasminogen activator inhibitor type 1 deficiency
| Age (y) | Sex | Bleeding phenotype | Lag time (min) | Thrombin peak time (min) | Thrombin peak height (nmol/L) | ETP (nmol/L) | Fibrin Lysis Time (min) | Plasmin peak height (nmol/L) | Plasmin potential (nmol/L) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Reference median a | 5,0 | 9,5 | 334,5 | 2073 | 30,3 | 10 | 89 | |||
| Reference 25 perc | 4.38 | 8,5 | 299 | 1878 | 21,8 | 5 | 36 | |||
| Reference 75 perc | 6,13 | 11,0 | 399 | 2214 | 41 | 17 | 202 | |||
| 1 | 24 | F | Minor | 2.5 | 7.8 | 220 | 2369 | 23.8 | 37 | 342 |
| 2 | 27 | F | Minor | 3.0 | 7.0 | 391 | 3376 | 24.8 | 47 | 474 |
| 3 | 16 | M | Minor | 2.5 | 6.5 | 226 | 2702 | 34.8 | 26.5 | 294 |
| 4 | 36 | F | Minor | 3.5 | 9.0 | 229 | 2256 | 31.5 | 27 | 331 |
| 5 | 33 | F | Minor | 3.0 | 8.3 | 237 | 2145 | 23.3 | 37.5 | 389 |
| 6 | 22 | M | Major | 3.0 | 8.0 | 188 | 1797 | 25.8 | 33 | 387 |
| 7 | 26 | F | Minor | 3.5 | 11.0 | 211 | 2655 | 35.0 | 31 | 348 |
| 8 | 37 | F | Minor | 2.5 | 6.8 | 264 | 1756 | 31.8 | 37.5 | 425 |
| 9 | 35 | M | Major | 3.5 | 9.0 | 248 | 1926 | 33.5 | 16 | 158 |
| 10 | 16 | F | Major | 3.0 | 7.5 | 234 | 1786 | 32.5 | 18 | 201 |
| Median | 3.0 | 7.9 | 231 | 2201 | 31.6 | 32.0 | 345 | |||
| 25 perc | 2.5 | 6.9 | 217 | 1794 | 24.5 | 24.4 | 271 | |||
| 75 perc | 3.5 | 9.0 | 252 | 2666 | 33.8 | 37.5 | 398 |
a
N = 53.