Table 1.
1. GV can be more readily assessed in clinical practice as a result of the increasing uptake of continuous and intermittently viewed glucose monitoring |
2. SD, CoV, AGP and TIR are commonly used to assess GV in clinical practice |
3. GV is a more clinically relevant marker of daily glucose control and hypoglycaemia risk than HbA1c |
4. We recommend that clinicians interpret glucose data in the context of mean glucose, SD, CoV, AGP and TIR; in T1DM, these often provide more meaningful data to inform therapeutic decisions than HbA1c |
5. Achieving widespread recognition of GV as a key metric of therapeutic success will require the following:
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6. Modern technologies (CGM, CSII, closed‐loop) and adjunctive agents (metformin, SGLT2) provide exciting opportunities to explore the impact of GV as a primary outcome of interest |
Abbreviations: AGP, ambulatory glucose profile; CGM, continuous glucose monitoring; CSII, continuous subcutaneous insulin infusion; GV, glycaemic variability; iCGM, integrated continuous glucose monitoring; SD, standard deviation; SGLT2, sodium‐glucose co‐transporter 2; T1DM, type 1 diabetes mellitus; TIR, time in range.