REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial and Virus Strains
Lenti-miR-132-3p	in-house	N/A
Lenti-scr	in-house	N/A
Lenti-miR-125b-5p	in-house	N/A
Chemicals, Peptides, and Recombinant Proteins
tetraisopropyl pyrophosphoramide	Sigma-Aldrich	T1505
Acetylthiocholine iodide	Sigma-Aldrich	A5751
ciliary neurotrophic factor	Sigma-Aldrich (Merck)	Cat#C3710
TRIzol	ThermoFisher Scientific	Cat#15596018
Critical Commercial Assays
Dual Luciferase Assay kit	Promega, WI USA	E1910
NEBNext Multiplex Small RNA Library Prep Set for Illumina	New England BioLabs	Cat#E7330
Deposited Data
Short RNA sequencing of LA-N-2 and LA-N-5	NCBI GEO	GSE132951
Short RNA sequencing of LA-N-2	NCBI GEO	GSE120520
Experimental Models: Cell Lines
U937	ATCC	CRL-1593.2; RRID:CVCL_0007
HEK293T	ATCC	CRL-3216; RRID:CVCL_0063
LA-N-2	DSMZ	Cat# ACC-671; RRID:CVCL_1829
LA-N-5	DSMZ	Cat# ACC-673; RRID:CVCL_0389
Oligonucleotides
vAChT primer FW+RV	Biorad	PrimePCR “qHsaCED0047922”
RPLP0 primer FW+RV	Biorad	PrimePCR “qHsaCED0038653”
Custom ChAT primer FW	ThermoFisher Scientific	N/A
Custom ChAT primer RV	ThermoFisher Scientific	N/A
Custom ACTB primer FW	ThermoFisher Scientific	N/A
Custom ACTB primer RV	ThermoFisher Scientific	N/A
Software and Algorithms
R version 3.5.3	https://www.r-project.org	N/A
miRExpress 2.1.4	http://mirexpress.mbc.nctu.edu.tw/index.php	N/A
DESeq2	http://www.bioconductor.org	N/A
Neo4j v3	https://.neo4j.com/	N/A
limma	http://www.bioconductor.org	N/A
circos	http://www.circos.ca	N/A
topGO	http://www.bioconductor.org	N/A
Other
Hsa-miR-132-3p plasmid	GeneCopoeia	MmiR3274-MR03
Negative control plasmid (scrambled control for pEZX-MR03)	GeneCopoeia	CmiR0001-MR03
microRNA Target Selection System plasmid	System Biosciences, CA, USA	#MS040-4xxA-1
EcoRI restriction enzyme	New England Biolabs	R0101
NotI restriction enzyme	New England Biolabs	R3189
plate reader	Tecan	GENios Pro Microplate Reader
CFX96 real-time PCR cycler	Biorad	Cat#1855196
NextSeq 550	Illumina	Cat#SY-415-1002