Table 1.

Baseline and post‐baseline % bleeding sites in (a) negative‐controlled studies; (b) positive‐controlled studies

Treatment	Baseline	Total	Post‐baseline
			Generally healthy (<10%)	Gingivitis (≥10%)
(a)
SnF2	<10%	436	430 (99%)	6 (1%)
	≥10%	444	301 (68%)	143 (32%)
Neg Control	<10%	365	332 (91%)	33 (9%)
	≥10%	386	139 (36%)	247 (64%)
(b)
SnF2	<10%	400	397 (99%)	3 (1%)
	≥10%	348	246 (71%)	102 (29%)
Pos Control	<10%	363	354 (98%)	9 (2%)
	≥10%	331	152 (46%)	179 (54%)

(a) Subjects with localized or generalized gingivitis had 3.7 times better odds (95% CI [2.8, 5.0]) of shifting to generally healthy (<10% bleeding) using SnF₂ versus a negative control.

(b) Subjects with localized or generalized gingivitis had 2.8 times better odds (95% CI [2.1, 3.9]) of shifting to generally healthy (<10% bleeding) using SnF₂ versus a positive control.