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. 2019 Aug 16;21(12):e13094. doi: 10.1111/cmi.13094

Figure 4.

Figure 4

IRE1α‐dependent degradation of genes is involved in Mycobacterium avium‐mediated apoptosis. Polymerase chain reaction (PCR) amplification of Bloc1s1 and St3gal5 from M. avium‐infected (a) RAW 264.7 cells or (c) bone marrow‐derived macrophages (BMDMs). (b) Bloc1s1 and St3gal5 mRNA levels were identified by real‐time PCR. (d) RAW 264.7 cells or (f) BMDMs were pretreated with 4μ8c (100 μM) and infected with M. avium. (e) mRNA levels of St3gal5 and Bloc1s1 by real‐time PCR. (g) RAW 264.7 cells were pretreated with 4μ8c and infected with M. avium for 24 hr. (h) RAW 264.7 cells were incubated with 4μ8c prior to infection with M. avium. Data are representative of three independent experiments (*p < .05, **p < .01, and ***p < .001)