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The endoplasmic reticulum (ER) stress response regulates the intracellular survival of Mycobacterium avium. Surviving intracellular M. avium were counted at 24 hr after infection. (a–c) RAW 264.7 cells or (d–f) BMDMs were pretreated with irestatin, NAC, or 4μ8c and infected with M. avium for 24 hr. Data are representative of at least three independent experiments (*p < .05, **p < .01, and ***p < .001)
