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Model structures of HgII bound to WT CueR at pH 8.0. Binding of HgII to CueR gives rise to an equilibrium between HgS2 and HgS3 when HgII:CueR <2, and to pure HgS2 coordination upon addition of 2 HgII ions per protein monomer. This can only be accounted for if the CCHH C‐terminal motif participates in the coordination of HgII, see the text for details.
