Figure 3.

Effects of CL316,243 on relative mRNA expression of A, mitochondrial and thermogenic genes in epididymal adipose tissues (EP) and B, Ucp1 in interscapular brown adipose tissue (BAT) in diabetic mice. Control, non‐diabetic mice; DC‐Con, diabetic control mice; DM + CL, diabetic mice treated with CL316,243; Pgc1α, peroxisome proliferator‐activated receptor‐γ coactivator‐1α; Atgl, adipose triglyceride lipase; Cox2, cytochrome oxidase subunit 2; Cd36, cluster of differentiation 36. C Representative western blot for Ucp1 protein in interscapular BAT and D, densitometric analysis. Data are the mean ± SEM (n = 7‐9 per group). *P < 0.05, **P < 0.01 compared with Control; ^† P < 0.05, ^†† P < 0.01 compared with the DM‐Con group. ^a P = 0.074, ^b P = 0.072 compared with Control