Sampling
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Sample characteristics
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Cases and controls
Underlying population: community, hospital
Consecutive sample or selection
If consecutive, attrition and reasons
Diagnosis and ascertainment
Diagnostic schema
Independent validation
Controls
Repeated measurement at follow‐up
Exclusion of current and history of diagnosis (i.e., screening)
Matching (e.g., age, sex)
Exclusion criteria
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Cases
Age of onset
Duration of illness
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Body composition
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Menstrual status
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Fat mass
Fat‐free mass
Bone mineral content and density
Ideally: Muscle mass
Measurement method: e.g., MRI, DXA, or BIA
Physical activity (ideally accelerometer data)
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Blood sampling
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Substances
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Blood sample type whole blood, serum, plasma
Fasting state
Fasting period
The time point of blood sampling
Pre‐analytics
Storage
Storage duration
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Dose and duration of
Contraceptives
Supplements & vitamins
Medication
Prescription
Over the counter
Laxatives
Illicit drugs
Alcohol consumption
Smoking behavior
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