Table 2.

Association of BMI‐GRS with overweight and obesity combined, obesity alone, and central obesity in univariate and multivariate models^a with OR (95% CI)

	Overweight + obesityb								Obesityc								Central obesityd
	Univariate				Multivariate				Univariate				Multivariate				Univariate				Multivariate
	OR	95% CI		P‐value	OR	95% CI		P‐value	OR	95% CI		P‐value	OR	95% CI		P‐value	OR	95% CI		P‐value	OR	95% CI		P‐value
BMI‐GRS, z‐score	1.38	1.20	1.58	<.001	1.39	1.21	1.60	<.001	1.40	1.08	1.81	.012	1.41	1.08	1.83	.011	1.18	1.00	1.40	.056	1.18	0.99	1.40	.064
Sex
Female					1.00								1.00								1.00
Male					1.63	1.23	2.15	.001					2.20	1.26	3.86	.006					1.81	1.27	2.58	.001
Parental language
Finnish					1.00								1.00								1.00
Swedish					1.10	0.63	1.93	.731					0.89	0.29	2.80	.846					0.69	0.33	1.47	.337
Other					0.41	0.15	1.14	.087					0.54	0.07	4.50	.571					0.72	0.23	2.30	.582
LTPA
≥7 h/wk					1.00								1.00								1.00
<7 h/wk					1.42	1.07	1.88	.015					1.47	0.86	2.52	.161					1.82	1.28	2.60	<.001
Sleep during week
Recommended					1.00								1.00								1.00
Less than recommended					1.58	0.81	3.08	.179					1.31	0.38	4.55	.674					1.71	0.78	3.75	.177
Eating habits
Healthy eating					1.00								1.00								1.00
Fruit and vegetable avoiders					0.99	0.64	1.53	.953					1.49	0.64	3.48	.357					1.53	0.90	2.60	.117
Unhealthy eating					1.15	0.85	1.55	.36					1.79	0.98	3.27	.06					1.48	1.01	2.18	.046

Abbreviations: BMI, body mass index; CI, confidence interval; GRS, genetic risk score; LTPA, leisure‐time physical activity; OR, odds ratio; PC, principal component.

^aAll models are adjusted for age, PC1 and PC2.

^bDefined with BMI z‐score greater than +1, n = 291.

^cDefined with BMI z‐score greater than +2, n = 61.

^dDefined with waist‐to‐height ratio ≥0.5, n = 158.