Table 1.
Characteristics | Sepsis | Septic Shock | Post‐Surgery | Healthy Controls |
---|---|---|---|---|
Age, mean (range) | 54 (29‐90) | 63 (19‐86) | 68 (22‐89) | 38 (26‐54) |
Gender (female/male) | 6/11 | 7/19 | 12/21 | 12/13 |
Site of infection, n (%) | ||||
Lung | 2 (12) | 5 (19) | 0 (0) | – |
Abdominal | 11 (65) | 14 (54) | 1 (3) | – |
Blood | 8 (47) | 7 (27) | 1 (3) | – |
Others | 4 (24) | 6 (23) | 1 (3) | – |
Laboratory values, mean ± SEM | ||||
WBC (109/L) | 13.2 ± 1.8 | 21.2 ± 2.8 | 10.1 ± 0.9 | – |
Platelets (109/L) | 187 ± 25.5 | 145 ± 16.7 | 174 ± 14.6 | – |
Lactate, (mmol/L) | 2.8 ± 0.5 | 3.5 ± 0.7 | 1.7 ± 0.3 | – |
CRP, (mg/L) | 136 ± 28.5 | 161.2 ± 17.5 | 39.4 ± 11.8 | – |
Procalcitonin, (ng/mL) | 26.3 ± 13.2 | 78.5 ± 19.1 | 0.9 ± 0.5 | – |
Creatinine, (umol/L) | 162 ± 51.5 | 170 ± 24.4 | 75 ± 5.2 | – |
Urea, (mmol/L) | 10.5 ± 1.7 | 14.4 ± 1.7 | 10.1 ± 4.6 | – |
ICU parameters, mean ± SEM | ||||
ICU days | 39 ± 9.6 | 29 ± 7.5 | 7 ± 2.7 | – |
Ventilation days | 4 ± 1.7 | 14 ± 6.6 | 3 ± 1.2 | – |
APACHE II | 15 ± 1.3 | 21 ± 1.7 | 11 ± 0.9 | |
SOFA score | 5 ± 0.6 | 10 ± 0.8 | 0.67 ± 0.2 | – |
Respiratory failure, n (%) | 5 (29) | 13 (48) | 1 (3) | – |
AKI, n (%) | 4 (24) | 13 (48) | 0 (0) | – |
28‐day mortality, n (%) | 0 (0) | 4 (15) | 1 (3) | – |
Data are presented as n (percentages), mean ± SEM.
Abbreviations: AKI, acute kidney injury; APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, C‐reactive protein; n, numbers; SEM, mean ± standard error of mean; SOFA, Sequential Organ Failure Assessment; WBC, white blood cell count.