Table 3.
Comparison of characteristics of those with and without peripheral neuropathy with a loss of protective sensationa. Figures are means (SD) unless otherwise stated
| Risk factor | Peripheral neuropathy | Difference | P‐value | N | |
|---|---|---|---|---|---|
| Absent | Present | (95% CI) | |||
| Median age (IQR) | 56.5 (48.8 to 56.5) | 68.4 (57.7 to 68.4) | −10.9 (−14.9 to −6.7) | < 0.0001 | 236 |
| Male (%) | 30.3 | 41.0 | −10.7 (−24.8 to 3.4) | 0.1261 | 236 |
| Known diabetesb (%) | 45.1 | 67.2 | −22.1 (−36.0 to −8.2) | 0.0030 | 236 |
| BMI (kgm−2) | 30.2 (6.6) | 30.0 (6.5) | 0.2 (−1.8 to 2.1) | 0.8627 | 227 |
| Waist circumference (cm) | 96.5 (13.3) | 100.9 (13.0) | −4.4 (−8.3 to ‐0.5) | 0.0274 | 231 |
| Treated blood pressure (%) | 48.6 | 62.3 | −13.7 (−28.0 to 0.5) | 0.0647 | 236 |
| Systolic blood pressure (mmHg) | 135.3 (19.0) | 141.2 (20.4) | −5.9 (−11.6 to −0.3) | 0.0407 | 236 |
| HDL (mmol l−1) | 1.3 (0.3) | 1.3 (0.3) | 0.0 (−0.1 to 0.1) | 0.7467 | 226 |
| Triglycerides (mmol l−1) | 1.1 (0.5) | 1.3 (0.6) | −0.2 (−0.3 to 0.0) | 0.0328 | 226 |
| HbA1c [mmol/mol (%)] | 54 (15), [7.1 (1.4)] | 56 (20), [7.3 (1.8)] | −2 (8 to 2), [−0.2 (−0.7 to 0.2)] | 0.3392 | 226 |
a
Peripheral neuropathy with a loss of protective sensation defined as at least one insensate site by monofilament testing and/or vibration perception threshold > 25 V.
b
Previously diagnosed diabetes.