Table 4.
Transfusion reactions reported for PCs and RBCs in patients who received PCs during the C‐PC and PI‐PC transfusion periods, assessed per transfusion
| Platelets | Red Blood Cells | |||||
|---|---|---|---|---|---|---|
| Conventional platelet period | INTERCEPT platelet period | OR (95% confidence interval) | Conventional platelet period | INTERCEPT platelet period | OR (95% confidence interval) | |
| Dates | (01/02/2006‐01/09/2011) | (01/10/2011‐1/17/2016) | (01/02/2006‐01/09/2011) | (01/10/2011‐1/17/2016) | ||
| Number of transfusions | 14,181 | 22,579 | 23,018 | 30,382 | ||
| Total reactions | 128 (0.90%) | 361 (1.60%) | 1.78 (1.46‐2.18) | 68 (0.30%) | 276 (0.91%) | 3.10 (2.37‐4.03) |
| Febrile nonhemolytic | 54 (0.38%) | 304 (1.35%) | 3.57 (2.67‐4.77) | 44 (0.19%) | 254 (0.84%) | 4.40 (3.20‐6.06) |
| Anaphylactic | 8 (0.06%) | 4 (0.02%) | NS | 1 (<0.01%) | 3 (0.01%) | NS |
| Mild allergic | 61 (0.43%) | 50 (0.22%) | 0.55 (0.35‐0.74) | 11 (0.05%) | 16 (0.05%) | NS |
| TACO | 1 (0.01%) | 2 (0.01%) | NS | 5 (0.02%) | 2 (0.01%) | NS |
| TRALI | 1 (0.01%) | 1 (0.01%) | NS | 0 (0.0%) | 0 (0.0%) | NS |
| Septic | 3 (0.02%) | 0 (0.0%) | NS | 2 (0.01%) | 0 (0.0%) | NS |
| Acute hemolytic | 0 (0.0%) | 0 (0.0%) | NS | 5 (0.02%) | 1 (0.01%) | NS |
NS = not significant; TACO = transfusion‐associated circulatory overload; TRALI = transfusion‐related acute lung injury.