Table 1.
Final list of outcomes considered for inclusion in ICHOM IA seta
| Outcome | Qualitative studies in which outcome was reported as important disease outcome | No. of IA conditions for which outcome is included in clinical trial core set | No. of IA conditions for which outcome was measured in ≥1 clinical trial, but not in core set | Working group members voted for inclusion (%) |
|---|---|---|---|---|
| Pain | 27 (96) | 3 | 1 | 100 |
| Physical function | 26 (93) | 4 | NA | 100 |
| Adverse events | 11 (39) | 0 | 4 | 95 |
| Fatigue | 23 (82) | 2 | 2 | 90 |
| Work/school ability and productivity | 14 (50) | 0 | 3 | 90 |
| Overall physical and mental health impact | NA | 4 | NA | 86 |
| Inflammatory disease activity | 6 (21) | 4 | NA | 84 |
| Participation restrictions | 18 (64) | 0 | 0 | 55 |
| Joint damage | 7 (25) | 2 | 1 | 45 |
| Mortality | 1 (4) | 0 | 0 | 40 |
| Psychological well‐being | 22 (79) | 0 | 0 | 35 |
| Sleep | 10 (36) | 0 | 2 | 35 |
| Coping & self‐management | 16 (57) | 0 | 0 | 33 |
| Financial impact | 3 (11) | 0 | 0 | 25 |
| Joint stiffness | 15 (54) | 0 | 4 | 20 |
| Joint range of motion | 0 (0) | 1 | 0 | 15 |
| Physical appearance | 7 (25) | 0 | 0 | 10 |
| Sexual functioning | 8 (29) | 0 | 0 | 10 |
| Cognitive functioning | 5 (18) | 0 | 0 | 5 |
| Fever | 0 (0) | 0 | 1 | 0 |
a
Values are the number (%) unless indicated otherwise. ICHOM = The International Consortium for Health Outcome Measurement; IA = inflammatory arthritis; NA = not applicable.