Table 1.
Clinical features and laboratory test results of 189 consecutive critically ill patients with acute kidney injury (AKI)
| Characteristics | All patients with AKI (n=189) | Survived group (n=119) | Non-survived group (n=70) | P value |
| Mean ages (year) (means±SD) |
63.33±18.294 | 61.73±18.997 | 66.06±16.813 | <0.001 |
| Gender (male), n (%) | 139 (73.5) | 88 (73.9) | 51 (72.9) | 0.937 |
| Gender (female), n (%) | 50 (26.5) | 31 (26.1) | 19 (27.1) | |
| SCr (μmol/L) (medians) | 165.0 (133.0, 238.0) | 166.0 (122.2, 359.2) | 165.0 (138.0, 215.5) | 0.716 |
| BUN (mmol/L) (medians) | 15.3 (9.8, 22.3) | 13.9 (9.2, 21.5) | 15.9 (10.8, 23.1) | 0.307 |
| Ua (medians) | 0.4 (0.3, 0.6) | 0.4 (0.3, 0.6) | 0.4 (0.3, 0.5) | 0.680 |
| ALT (IU/L) (medians) | 33.0 (20.0, 65.5) | 41.0 (25.0, 85.0) | 26.5 (17.0, 52.8) | 0.004 |
| TB (medians) | 12.1 (8.3, 20.9) | 12.3 (8.2, 18.7) | 12.0 (9.2, 20.9) | 0.870 |
| Prealbumin (mg/L) (medians) | 135.0 (95.0, 196.0) | 134.5 (98.5, 176.2) | 135.0 (94.0, 206.0) | 0.699 |
| Blood glucose (mmol/L) (medians) | 6.9 (5.4, 9.5) | 7.3 (5.5, 10.1) | 6.5 (5.4, 8.5) | 0.283 |
| C reactive protein (μg/L) (medians) | 69.1 (18.6, 122.0) | 69.1 (20.0, 132.5) | 69.7 (15.7, 119.0) | 0.363 |
| TG (medians) | 1.6 (1.0, 2.8) | 1.9 (1.2, 3.2) | 1.4 (0.9, 1.9) | 0.072 |
| CHO (medians) | 3.5 (2.7, 4.4) | 3.6 (2.8, 4.3) | 3.4 (2.6, 4.4) | 0.512 |
| LDL (medians) | 2.4 (1.7, 3.0) | 2.4 (1.8, 2.9) | 2.4 (1.6, 3.0) | 0.802 |
| Albumin (g/L) (means±SD) |
32.3±6.9 | 31.6±7.2 | 32.9±6.6 | 0.215 |
| HDL (means±SD) | 0.8±0.4 | 0.7±0.4 | 0.9±0.4 | 0.091 |
| Na (mmol/L) (medians) | 140.0 (136.0, 148.8) | 140.0 (135.0, 149.0) | 140.0 (137.0, 147.0) | 0.791 |
| Cl (mmol/L) (medians) | 103.0 (98.0, 111.0) | 103.0 (98.0, 113.0) | 102.0 (97.0, 111.0) | 0.582 |
| K (mmol/L) (means±SD) | 4.2±0.9 | 4.2±0.9 | 4.2±0.9 | 0.555 |
| Ca (mmol/L) (means±SD) | 2.1±0.3 | 2.0±0.3 | 2.1±0.2 | 0.505 |
| P (mmol/L) (medians) | 1.2 (0.9, 1.6) | 1.4 (1.0, 1.7) | 1.2 (0.8, 1.4) | 0.042 |
| WCC (×103/μL) (medians) | 11.5 (7.7, 16.7) | 11.7 (9.1, 16.4) | 11.0 (7.0, 16.9) | 0.490 |
| RBC (×1012/L) (means±SD) | 3.7±0.9 | 3.8±0.9 | 3.7±0.8 | 0.227 |
| HCT (means±SD) | 33.6±7.2 | 34.0±8.3 | 33.2±6.1 | 0.495 |
| Platelets(×109/L) (means±SD) | 155.5±95.0 | 167.0±109.0 | 144.9±79.2 | 0.112 |
| Hemoglobin (×g/dL) (means±SD) | 111.0±24.5 | 112.5±28.0 | 109.6±20.8 | 0.420 |
| MO (means±SD) | 7.0±3.1 | 6.9±3.1 | 7.1±3.1 | 0.577 |
| Stay in hospital (days) (medians) | 20.0 (12.0, 36.5) | 18.0 (13.0, 29.0) | 22.5 (12.0, 51.0) | 0.038 |
| APACHE II scores (medians) |
16.00 (12.0, 26.0) | 16.0 (10.0, 23.5) | 17.0 (13.0, 26.0) | 0.099 |
| ATN-ISI scores (medians) | 0.335 (0.21, 0.58) | 0.28 (0.15, 0.59) | 0.34 (0.24, 0.58) | 0.032 |
| SAPS II scores (medians) | 43.0 (31.0, 60.5) | 42.5 (24.0, 57.25) | 44.0 (35.0, 62.0) | 0.048 |
| SOFA scores (medians) | 6.0 (3.0, 11.0) | 6.0 (4.0, 12.0) | 6.0 (3.0, 11.0) | 0.703 |
| RIFLE | 0.272 | |||
| Fc, n (%) | 55 (30.4) | 34 (29.1) | 21 (32.8) | |
| Ic, n (%) | 47 (26.0) | 27 (49.0) | 20 (31.2) | |
| Rc, n (%) | 79 (43.6) | 56 (47.9) | 23 (35.9) |
The various parameters were obtained within the first 24 hours following admission.
ALT, alanine amino transaminase; APACHE II, Acute Physiology and Chronic Health Evaluation version II; ATN-ISI, Acute Tubular Necrosis Individual Severity Index; BUN, serum urea nitrogen; Ca, serum calcium; Cho, serum total cholesterol Cl, serum chlorine; Fc, F stage of the Risk, Injury, Failure, Loss, or End-stage kidney disease criteria; HDL, High density lipoprotein; Ic, I stage of the Risk, Injury, Failure, Loss, or End-stage kidney disease criteria; K, serum potassium; LDL, low density lipoprotein; MO, monocyte; Na, serum sodium; P, serum phosphorus; RBC, total blood count of red blood cell; RIFLE, Risk, Injury, Failure, Loss, or End-stage kidney disease; Rc, R stage of the Risk, Injury, Failure, Loss, or End-stage kidney disease criteria; SAPS II, Simplified Acute Physiology Score version II; SCr, serum creatinine; SOFA, Sepsis-related Organ Failure Assessment; WBC, total blood count of white cell count; TB, total protein; TG, triglyceride; Ua, uric acid;