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| Mutation | I-Mutant 3.0 | NetSurfP | |||
| DDG | Stability | Class | Relative | Absolute | |
| value | assignment | surface | surface | ||
| accessibility | accessibility | ||||
| (RSA) | (ASA) | ||||
| S646F | -0.71 | Decrease | Exposed | 0.638909 | 74.88009 |
| F78L | 0.62 | Increase | Buried | 0.032513 | 6.525376 |
| Q644R | -1.39 | Decrease | Exposed | 0.44884 | 80.16283 |
