Figure 1.

miR‐130b and miR‐21 are significantly upregulated in liver cancer tissues and serum samples. (a) The relative expression levels of miR‐130b and miR‐21 was significantly higher in HCC tissues than in adjacent non‐cancerous tissues, respectively. U6 was used as an internal normalization control. *p < .05, versus Adjacent non‐cancerous group (n = 46). (b) Serum relative expression of miR‐130b and miR‐21 in HCC groups (n = 46) and healthy controls (n = 55) (p < .05). U6 was used as an internal normalization control. (c) Correlation of miR‐130b expression between serum and tumor tissues (r = .797, p < .001). (d) Correlation of miR‐21 expression between serum and tumor tissues (r = .825, p < .001). The analysis of miR‐130b (e) and miR‐21 (f) expression in serum were significantly declined in postoperative HCC patients compared with that in preoperative patients (n = 33). Each sample was analyzed in triplicate