Table 3.

Predicted transcription factor binding sites on the CLN3 gene

Position Relative to TSS	Transcription factor	p‐value	Length
−329/−123	E2F3	6.9E‐05/5.6E‐07	14
−323	E2F4	8.50E‐05	10
−734	EGR2	5.90E‐05	14
−549	ELF1	3.40E‐06	12
−1,396	ESR1	3.50E‐05	19
−1,344/−672/−214	ESRRA	7.4E‐05/‐9.10E‐05/3.05E‐05	10
−919	FOXA1	1.40E‐06	14
−915	Foxa2	8.20E‐08	11
−131	FOXC1	5.00E‐05	7
−1,276	Foxd3	3.20E‐05	11
−777	FOXI1	9.80E‐05	11
−1,469/−1,271/−807	FOXP1	3.7E‐05/2.2E‐05/3.00E‐05	14
−545	GABPA	5.50E‐06	10
−1,364	Gata4	4.40E‐05	10
−603/−407/−388	Klf4	1.4E‐05/3.60E‐05/5.00E‐07	9
−1,222	Meis1	9.90E‐05	14
−83	NHLH1	7.50E‐05	11
−1,349/−677	NR2F1	5.4E‐05/2.00E‐05	13
−172	NRF1	9.60E‐05	10
−495	Pax2	9.70E‐05	7
−1,468	Pax4	2.80E‐05	29
−1,493/−1,102	PAX5	2.2E‐06/4.40E‐05	18
−1,317	PBX1	4.60E‐05	11
−230	PLAG1	1.60E‐06	13
−1,285	POU2F2	3.90E‐05	12
−1,253	PRDM1	8.20E‐06	14
−1,136	Rfx1	7.60E‐05	13
−1,167	RFX5	6.30E‐05	14
−603/−412/−393/−123	SP2	1.30E‐05/1.90E‐05/6.80E‐05/4.60E‐06	14
−715/−305	Tcfcp2l1	8.90E‐05/5.70E‐05	13
−1,409/−434	TFAP2C	5.70E‐05/1.60E‐05	14
−711	THAP1	4.60E‐05	8
−308	TP63	2.70E‐05	19
−786/−494/−267	USF2	8.00E‐05/7.60E‐06/7.20E‐05	10
−242	ZBTB33	8.80E‐05	14
−83	ZEB1	4.80E‐05	8
−433	Zfx	2.60E‐05	13

Transcription Factors from MetaCore from Clarivate Analytics (Ekins, Nikolsky, Bugrim, Kirillov, & Nikolskaya, 2007).